PicoSure® Pro

PicoSure Pro is a state-of-the-art picosecond laser platform from Cynosure that delivers ultra-short bursts of laser energy measured in trillionths of a second (picoseconds). This extremely fast delivery reduces heat buildup in the skin while breaking up unwanted pigment, tattoo ink, and other target chromophores more effectively than older generation lasers. PicoSure Pro is FDA-cleared for treating a range of skin concerns, including stubborn pigmentary disorders and visible signs of aging, and offers powerful tattoo removal capability when equipped with additional wavelengths.

Technology and How It Works

PicoSure Pro uses a primary 755 nm picosecond laser wavelength that is highly effective at targeting melanin in pigmented lesions and tattoo ink. Because the pulses are delivered so quickly, the laser creates a photomechanical or pressure wave effect rather than relying on heat, which helps minimize thermal damage to surrounding tissue and supports faster recovery.

The system includes one zoom handpiece (2–6 mm) and multiple fixed handpieces (5 mm, 6 mm, 8 mm, and 10 mm) with adjustable fluence settings to customize treatment for different indications and skin types. A Platinum Focus™ lens enhances skin revitalization treatments with virtually no downtime, and additional 532 nm and 1064 nm wavelengths can be added for advanced tattoo removal protocols.

Clinical Applications and Indications

PicoSure Pro is indicated for a broad range of cosmetic and dermatologic treatments, making it a highly versatile platform for aesthetic practices:

Pigment Correction — Effectively lightens or clears unwanted pigmented lesions, sun spots, age spots, and benign pigmented conditions. It is the only picosecond laser device FDA-cleared to treat melasma pigment, nevus of Ota, and Hori’s nevus in all skin types, including darker tones when used with appropriate settings.

Skin Revitalization — Improves overall skin tone and texture by stimulating collagen and elastin production. Patients often see a brighter, more even complexion, reduced pore size, and smoother skin with minimal recovery time.

Fine Lines, Wrinkles, and Acne Scars — Picosecond pulses help reduce fine lines, wrinkles, and acne scar visibility through controlled dermal remodeling.

Tattoo Removal — When equipped with optional 532 nm and 1064 nm wavelengths, PicoSure Pro can treat a wide range of tattoo ink colors including difficult “sunset” tones such as red, yellow, and orange as well as traditional black, blue, and green. Técnica options such as turbo mode enhance performance on stubborn inks.

Patient Experience

Treatments with PicoSure Pro are generally quick and comfortable. Because the pulses act in picoseconds rather than nanoseconds, heat buildup in the skin is reduced, which helps lower the risk of thermal injury and shorten recovery time compared with traditional lasers. Most procedures on pigment and skin texture take just minutes, and many patients return to daily activities with little to no downtime. Mild redness or light sensitivity immediately post-treatment is common and usually resolves within a day.

Average Treatment Pricing (Typical Practice)

Pricing for PicoSure Pro treatments varies by clinic location and service structure:

Skin Revitalization and Pigment Correction — Single sessions are often priced between $300 and $600 USD depending on treated area size and indication. Many clinics package a series of 3–6 treatments for optimal results, with total package pricing often ranging from $1,000 to $3,000 USD or more.

Tattoo Removal — Pricing is typically based on tattoo size and complexity. Small tattoos may start around $200–$400 USD per session, while larger or multi-color tattoos often cost $700–$1,500 USD per session or higher. Most tattoos require multiple sessions for substantial clearance.

These price points support significant revenue per treatment and encourage patient commitment through package offerings.

Practice Benefits and Revenue Potential

PicoSure Pro is a high-value, multi-indication platform that supports a wide range of treatment protocols from aesthetic rejuvenation to corrective dermatologic services. Short session durations and strong patient demand for visible results help clinics maximize patient throughput and treatment revenue.

Because the laser handles multiple cosmetic needs with precision and low downtime, practices benefit from increased patient satisfaction and recurring appointments. Package pricing, maintenance treatments, and combination protocols with other services further drive clinic revenue and long-term patient relationships.

Safety and Versatility

PicoSure Pro’s picosecond technology reduces the risk of thermal damage compared with slower pulse lasers and broadens safe applicability across multiple Fitzpatrick skin types when used by trained providers. FDA clearance for challenging pigmentary conditions underscores its clinical credibility. A thorough consultation and individualized setting selection are essential to optimize outcomes and minimize potential side effects.

Conclusion

PicoSure Pro is an advanced picosecond laser platform that elevates aesthetic and dermatologic care by delivering fast, effective treatments for pigmentation, skin texture, acne scarring, fine lines, and tattoo removal with minimal downtime. Its precision, versatility, and clinical validation make it a transformative device for practices aiming to deliver high-impact cosmetic results with strong revenue potential.